What is EPCS? Electronic Prescribing for Controlled Substances

What is EPCS? How Does it Help with Prescription Safety?

Fight substance abuse and comply with state and federal Electronic Prescribing for Controlled Substances (EPCS) mandates with EPCS-certified healthcare software.

EPCS helps to saves lives

The Centers for Disease Control and Prevention report that opioid-related deaths fell by 4% from 2017 to 2018. While that’s good news, more than 67,000 lost their lives to opioid overdoses in 2018, the leading cause of injury-related death in the U.S. And 70% of those deaths were due to prescription or illicit opioids. One of the most effective ways to combat opioid abuse is Electronic Prescribing of Controlled Substances (EPCS). Eliminating paper prescriptions helps reduce prescription fraud, forgery, and “doctor shopping” for controlled substances. Also, electronic prescriptions are more easily tracked and monitored by physicians.

A majority of U.S. states have implemented laws requiring EPCS or have laws taking effect in the next several years. In addition, the SUPPORT for Patients and Communities Act of 2018  requires e-prescribing for controlled substances for Medicare patients. The Electronic Prescribing for Controlled Substances (EPCS) legislation took effect on January 1, 2022. On January 1, 2023, EPCS will be enforced for Medicare Part D and Medicare Advantage prescription drug plans.

Learn more from the Ultimate Guide to EPCS mandates.

Which states require EPCS?

  • Upcoming 2024 Mandate
  • Current Mandate
  • No Mandate

What is a PDMP?

All U.S. states now have an electronic database known as a prescription drug monitoring program (PMP or PDMP). A PDMP tracks and provides a history of prescriptions and controlled substances, to help reduce the misuse of controlled substances.

Many states require prescribers to check their state’s PDMP when prescribing controlled substances. See if this is required in your state. Our eRx will connect directly to your state’s PDMP!

How to achieve prescribing workflow efficiency? ERX!

Since 1999, RXNT has pioneered digital Electronic Prescribing Software—for independent ambulatory practices and prescribers—has been EPCS-certified by the DEA since the 2010 legislation was enacted. RXNT's award-winning software satisfies both Federal and State regulations and connects directly to your state’s Prescription Drug Monitoring Program (PDMP) or Prescription Monitoring Program (PMP).

RXNT’s affordable
e-prescribing software is EPCS-certified and has built-in features that make prescribing easier and safer:

Mobile App

Free mobile app (iOS and Android) lets you prescribe 24/7 from anywhere.

Unlimited Users

No license fee for non-prescribing staff.

Certified Solution

Surescripts and DEA-certified for peace of mind.

by the DEA

Allows you to easily comply with EPCS for class II-V medications.

Patient-Specific Formularies

Determine the most clinically appropriate and cost-effective medications.

Electronic Prior Authorizations (ePA)

Eliminates time-consuming paper forms, faxes, and phone calls.

Real-Time Medication History

Determine compliance, improve adherence, and reduce adverse drug interactions.

Drug and Allergy Interaction Checks

Improve safety and quality with drug-drug, drug-allergy and drug-diagnosis interaction checks.

Comprehensive Reporting

Manage your business with customizable and actionable reports.

Ready to get started? See our EPCS-certified eRx software in action!

Get a first-hand look at how our integrated, EPCS-certified eRx software will improve how you prescribe and help you satisfy all state and federal controlled medication legislation with an easy, virtual demo. Our friendly, no-pressure customer advisors will answer any questions and help evaluate your needs.

Used in healthcare organizations of all sizes, from small family clinics to large, multi-specialty practices—we offer flexible pricing options to make our tools accessible to almost any practice. Every product is backed by 24/7 cloud-based access, premium in-house support, and regular system upgrades.

Badge for Inc. Magazine's 5000 Fastest-Growing Private Companies in America for 2020
SA Frontrunners Badge 22
RXNT Recognized as Digital.com's Best E-Prescribing EPCS eRx Software of 2021
Gartner Capterra Best Value 2021 For Patient Portal, Part of RXNT's EHR Software with EPCS-Certified ERX and Scheduling

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