Electronic Prescribing of Controlled Substances

EPCS Header

RxNT|EPCS is a certified solution which enables prescribers to send controlled substances electronically, directly from the point of patient care. Electronic prescribing of controlled substances (EPCS) was legalized at the national level in 2010 by the Drug Enforcement Agency (DEA), and since then all 50 states have followed suit. With RxNT|EPCS, prescribers can undertake DEA required identity proofing and select a token needed to fulfill the DEA’s two-step authentication requirement for EPCS.

$25 Per Provider Per Year*

What are Providers saying about RxNT|EPCS?

Ease of use, security, dependability, together with an amazing support team have made RxNT a great EPCS provider.  The RxNT staff has followed through with every detail in order to make my experience and my patients’ experience one of security and confidence. Thanks to RxNT’s reliability, I can dedicate my time to my passion of being a doctor.
Jimmy Salas-Rushford, MD | New York and Puerto Rico – Internal Medicine

Benefits of e-Prescribing

Benefits of Electronic Prescribing of Controlled Substances (EPCS):


Ability to prescribe C-IIs through CVs

Improve safety and patient care

Prevent prescription drug abuse

Reduce risk of fraud and abuse

Reduce wrongful death lawsuits

Identify patients who are doctor shopping

Secure transmission to the pharmacy

Reporting tools in the event of an audit

Unique pin and e-signature


All-in-one e-prescribing solution

EPCS certified Android and iOS applications

Hard token options available (physical or downloadable)

DEA, NIST, and Surescripts compliant

Frequently Asked Questions about RxNT|EPCS

Q: Can I e-Prescribe controlled substances from my mobile device?

Yes. If you can access the internet, you can access RxNT|EPCS. RxNT even has an iOS app and has recently introduced the first EPCS-certified Android app to the market.

Q: How does the ID proofing process work with RxNT|EPCS?

RxNT|EPCS includes a link to our ID proofing partner, Experian. Click on the link to answer a series of questions meant to confirm your identity. After ID proofing is complete, you are issued a password (something you know) and a token (something you have) to meet the two-factor authentication required by the Drug Enforcement Agency (DEA) to prescribe controlled substances. RxNT provides prescribers two options for the token through our partner, Safenet: a physical device or a downloadable application.

Q: I have activated my token but there is a warning message showing. How do I get rid of this?

A: Ensure that you have contacted an RxNT Team Member to activate your token. The account must update overnight before you can begin to utilize your token.

Q: I have sent in my paperwork requesting my token. Why do I not have it yet?

A: Before RxNT can send you your token, you need to complete the Identity Proofing Test. This is located within your RxNT Account and steps were sent to you in your “RxNT Getting Started” email.

Steps to access ID Proofing Test:

  1. Go to the “Utilities” tab
  2. Select “Activate EPCS”

Once you successfully authenticate your identity, RxNT will be notified to begin processing your token.

*See Pricing for More Details

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